The best cannabis strains for weight loss are determined by their chemical composition. For a strain to be considered fit for weight loss, it must effectively suppress your appetite and keep you active.

The cannabinoids, terpenes, and flavonoids in every cannabis strain dictate how to modulate the endocannabinoid system (ECS) and the subsequent responses.


Key Takeaways

  • Cannabis has crucial cannabinoids and terpenes that could influence food cravings and metabolism.
  • The best weight-loss strains have significant CBD and THCV levels, the popular appetite-suppressing cannabinoids.
  • For effective weight management, you must incorporate other best practices, such as eating a balanced diet and exercising regularly.

But How Does Cannabis Contribute to Weight Loss?

Weed Smoking Accessories

Smoking weed with a Vortex Gravity bong

Cannabis has Cannabidiol (CBD) and Tetrahydrocannabivarin (THCV) cannabinoids, which are known to significantly impact the ECS and modulate hormone production. Studies show that these two cannabinoids block the CB1 receptors, stopping further stimulation from Tetrahydrocannabinol (THC).

Stopping THC effects means stopping the psychoactive effects that lead to couch lock and inactivity. It also means blocking mediation between the effects of THC and other endocannabinoids that stimulate appetite and fat accumulation.

In addition to stopping THC on its tracks, CBD and THCV enhance production of hormones like anandamide and resistin to improve metabolic health and reduce the risk of obesity.

So, a cannabis strain with high levels of CBD and THCV can be ideal for weight loss.

Similarly, the cannabis strain must be rich in terpenes, that contribute to weight management and fitness. Terpenes like Quercetin, Apigenin, and Humulene suppresses the hormone ghrelin, which is responsible for hunger signals. As a result, signs of hunger and stress fade away, leaving you relaxed and with no cravings for food.

This guide should not be used as a substitute for medical advice, diagnosis, or treatment. Consult a medical doctor before you make any health and well-being decisions.

The Best Cannabis Strains for Weight Loss

Durban Poison, ACDC, Jack the Ripper, Doug’s Varin, and Harlequin are some of the best cannabis strains for weight loss because they have favorable chemical composition to prevent the munchies effect and keep you active.

So, find out how these strains stand out for appetite boosting.

  1. Durban Poison

The Durban Poison Cannabis Strain

Durban Poison

Durban Poison cannabis strain is pure sativa that keeps you energetic and uplifted throughout your day. Unlike Indica dominant strains known for overwhelming sedation, consuming a pure Sativa like Durban Poison keeps you physically active, a key factor in weight management.

Although the 25% THC level and about zero CBD may not be ideal for weight management, Durban Poison has a higher-than-average THCV level (1.8%) enough to possibly keep any munchies effects in check.

Besides counteracting THC’s munchies effects, THCV is known to aid insulin sensitivity and glucose metabolism. Therefore, despite being notably psychoactive, Durban Poison can reduce hunger and aid calorie intake.

In addition, Durban Poison has Humulene terpene that, besides offering a pleasant aroma, can suppress appetite through a synergistic cooperation with THCV.

  1. Jack The Ripper (JTR)

cannabis strain

JTR strain

JTR is a sativa-dominant hybrid cross of Jack’s Cleaner and Space Queen strains. Its ideal for weight loss due to the energizing effects and the presence of crucial cannabinoids and terpenes.

In fact, Jack the Ripper is one of the most potent THCV strains available, with the cannabinoid reaching a high of 5%. Moreover, the THC content in this strain is relatively low at 15% and about 1% CBD.

This level of THCV and CBD is enough to counter THC’s munchies effect by blocking receptors and preventing ghrelin release. Together with CBD, THCV can enhance fat expenditure and oxidation, which are crucial for calorie burn.

JTR also has key terpenes for weight loss, albeit in trace amounts. Terpenes such as Humulene and Quercetin, enhance THCV and CBD’s work of blocking hunger hormones and increasing the production of satiety hormones.

RELATED: 5 Best Wake And Bake Cannabis Strains

  1. Doug’s Varin Cannabis Strain

Cannabis strain placed on a surface

Doug’s Varin Cannabis

Doug’s Farm crossed the Harlequin and That Landrace to make a pure Sativa strain with the highest THCV percentage known so far. With about 15% THCV and about 19% THC, Doug’s Varin offers a balanced high that keeps you creative and focused without experiencing any pangs of hunger or sedation.

Besides that, Doug’s Varin has Humulene and Apigenin terpenes, common in apples and chamomile. Combined with the high THCV, these terpenes can block receptors in the ECS, halting any THC impact that can bring on the munchies or keep you sedated.

  1. Harlequin Cannabis Strain

 Cannabis Strain

Harlequin Cannabis Strain

Harlequin cannabis is another top strain crafted to contain high levels of CBD. Breeders crossed the Nepali Indica, Colombian Gold, Thai, and Swiss Landrace strains to produce a strain that provided clear-headed effects without intoxication or sedation.

Harlequin boats CBD amount of about 10% and THC of about 5%. As a result, it offers high levels of therapeutic effects such as pain alleviation, anti-inflammation, and anti-paranoia. CBD’s non-psychoactive properties mean you can consume Harlequin cannabis and remain focused and active.

Another critical component in the Harlequin weed strain that makes it ideal for weight loss is the presence of the Apigenin terpene. In addition to offering anti-anxiety and anti-cancer effects, this terpene modulates metabolism genes, enhancing energy use in your body.

Such a combination contributes to an ultimate entourage effect critical in weight loss endeavors.

  1. ACDC Cannabis Strain

cannabis strains for weight loss

Cannabis can help you lose weight

ACDC is short for Alternative Cannabinoid Dietary Cannabis, a strain initially bred by Northern California physician Dr. William Courtney.

Dr. Williman looked for a way to benefit from marijuana without intoxication, hence the strain’s high CBD content (20%) compared to THC (1%). So, with this strain, you won’t have to worry about psychoactivity or the hunger pangs caused by THC.

The high CBD levels, THCV traces, and the 50:50 Indica Sativa ratio provide a balanced round of effects that keep you active without leading to drowsiness. Besides, the ACDC cannabis strain is rich in Humulene terpene, which suppresses appetite through the PPAR -alpha receptor.

RELATED: 5 Best Cannabis Strains For Appetite Boost

Cannabis And Weight Management

While these cannabis strains have proven to promote weight loss, you need to do more than just cannabis to get the best results. Other best practices include eating a balanced diet and exercising regularly.

Most importantly, you should consult your physician before introducing cannabis to our weight loss routine.